SEVERE TYPE 1 UPGRADING LEPROSY REACTION IN A RENAL TRANSPLANT RECIPIENT: A PARADOXICAL MANIFESTATION ASSOCIATED WITH DEFICIENCY OF ANTIGEN-SPECIFIC REGULATORY T-CELLS?

Severe type 1 upgrading leprosy reaction in a renal transplant recipient: a paradoxical manifestation associated with deficiency of antigen-specific regulatory T-cells?

Abstract Background Due to its chronic subclinical course and large spectrum of manifestations, leprosy often represents a diagnostic challenge.Even with proper anti-mycobacteria treatment, leprosy follow up remains challenging: almost half of leprosy patients may develop reaction episodes.Leprosy is an infrequent complication of solid organ transp

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